We have seen a rash of injuries over the first five weeks, highlighted by Indy’s reigning rushing champ Jonathan Taylor (vs. Jaguars in Week 6). Taylor (ankle) missed the Colts’ Week 5 tilt with the Broncos, but he hopes to return in a juicy divisional matchup with Jacksonville. With Nyheim Hines (concussion) also dinged up, it could be the Deon Jackson show. 

As we always say, injuries are a curse to some but a blessing for others. Veteran Seahawks back Rashaad Penny (tibia) might have suffered a season-ending leg injury over the weekend, paving the way for rookie Kenneth Walker III (vs. Cardinals) to break off a massive TD run. After New England ruled Damien Harris (hamstring) out, Rhamondre Stevenson (@ Browns) stepped up and rumbled over the Lions for 161 yards. Both KW3 and ‘Mondre have massive PPR upside, as their coaches have lauded their hands and feet during their young professional careers. Eno Benjamin (@ Seahawks) would also be a great running and receiving option this week if James Conner (ribs) can’t go.

WEEK 6 PPR RANKINGS:QBs | WRs | TEs | D/STs | Kickers

Other backs who remain multifaceted offensive threats include Devin Singletary (@ Chiefs), Melvin Gordon III (@ Chargers), and JK Dobbins (@ Giants). It’s safe to say we can also add Jets rookie Breece Hall (@ Packers) to this list despite the tough matchup. Hall has been explosive over the past two weeks and should at least supplant Michael Carter on Gang Green’s RB depth chart. Similarly, Travis Etienne (@ Colts) is coming off his best game and is in play in PPR leagues in a decent matchup against Indianapolis. James Robinson is still a safer option, though.

WEEK 6 STANDARD RANKINGS:QBs | RBs | WRs | TEs | D/STs | Kickers

Raheem Mostert (vs. Vikings), who’s dominating touches over Chase Edmonds, is trending up, but that’s not the case for all “RB1s.” Cam Akers (vs. Panthers) has taken over in L.A., but he’s struggled all year and is merely a ho-hum flex against Carolina. Brian Robinson Jr. (@ Bears) should continue ramping up, but the crowded Commanders’ RB room limits his value in a favorable matchup against Chicago. Tyler Allgeier (vs. 49ers) is still ceding some carries to Caleb Huntley, and Damien Williams (ribs) might return to eat into Allgeier’s playing time even more. Given the matchup, it’s tough to trust any Falcons’ back.

WEEK 6 DFS: Best stacks | Best values

Because Derrick Henry, Jamaal Williams and D’Andre Swift, Dameon Pierce, and Josh Jacobs are off this week, some fantasy owners will have to dig deep for their RB2s or flexes. That might mean playing Najee Harris (vs. Buccaneers), Clyde Edwards-Helaire (vs. Bills), or both Ezekiel Elliott and Tony Pollard (@ Eagles) in tough matchups or hoping for a bunch of catches from Kareem Hunt (vs. Patriots), Rachaad White (@ Steelers) or Hines (vs. Jaguars) if he plays.

WEEK 6 DFS LINEUPS: FanDuel | DraftKings

There aren’t any perfect answers when faced with decisions like this. In PPR leagues, you can usually find higher-floor guys based simply on targets, but sometimes you just have to trust the touches and hope for a TD.

WEEK 6 FANTASY PICKS: Sleepers | Busts | Start ’em, sit ’em

Note: We’ll be updating these RB PPR rankings throughout the week, so check back for analysis and the latest player movement.

Week 6 fantasy RB PPR rankings

Rankings based on full-point PPR scoring leagues

Rank    Player 1    Saquon Barkley, Giants vs. Ravens 2    Dalvin Cook, Vikings @ Dolphins 3    Austin Ekeler, Chargers vs. Broncos 4    Christian McCaffrey, Panthers @ Rams 5    Leonard Fournette, Buccaneers @ Steelers 6    Nick Chubb, Browns vs. Patriots 7    Alvin Kamara, Saints vs. Bengals 8    Joe Mixon, Bengals @ Saints 9    Aaron Jones, Packers vs. Jets 10    Rhamondre Stevenson, Patriots @ Browns 11    Kenneth Walker III, Seahawks vs. Cardinals 12    Devin Singletary, Bills @ Chiefs 13    Melvin Gordon III, Broncos @ Chargers 14    Eno Benjamin, Cardinals @ Seahawks 15    AJ Dillon, Packers vs. Jets 16    James Robinson, Jaguars @ Colts 17    JK Dobbins, Ravens @ Giants 18    David Montgomery, Bears vs. Commanders 19    Jeff Wilson Jr., 49ers @ Falcons 20    Raheem Mostert, Dolphins vs. Vikings 21    Miles Sanders, Eagles vs. Cowboys 22    Darrell Henderson Jr., Rams vs. Panthers 23    Deon Jackson, Colts vs. Jaguars 24    Clyde Edwards-Helaire, Chiefs vs. Bills 25    Ezekiel Elliott, Cowboys @ Eagles 26    Breece Hall, Jets @ Packers 27    Najee Harris, Steelers vs. Buccaneers 28    Travis Etienne Jr., Jaguars @ Colts 29    Tony Pollard, Cowboys @ Eagles 30    Kareem Hunt, Browns vs. Patriots 31    Khalil Herbert, Bears vs. Commanders 32    Brian Robinson Jr., Commanders @ Bears 33    Michael Carter, Jets @ Packers 34    Mike Boone, Broncos @ Chargers 35    Rachaad White, Buccaneers @ Steelers 36    Tyler Allgeier, Falcons vs. 49ers 37    Phillip Lindsay, Colts vs. Jaguars 38    Caleb Huntley, Falcons vs. 49ers 39    Chase Edmonds, Dolphins vs. Vikings 40    Kenneth Gainwell, Eagles vs. Cowboys 41    Jerick McKinnon, Chiefs vs. Bills 42    Mark Ingram, Saints vs. Bengals 43    Antonio Gibson, Commanders @ Bears 44    J.D. McKissic, Commanders @ Bears 45    DeeJay Dallas, Seahawks vs. Cardinals 46    Tyrion Davis-Price, 49ers @ Falcons 47    Zack Moss, Bills @ Chiefs 48    Kenyan Drake, Ravens @ Giants 49    Isiah Pacheco, Chiefs vs. Bills 50    Samaje Perine, Bengals @ Saints 51    Jaylen Warren, Steelers vs. Buccaneers 52    Joshua Kelley, Chargers vs. Broncos 53    Malcolm Brown, Rams vs. Panthers 54    Latavius Murray, Broncos @ Chargers 55    Alexander Mattison, Vikings @ Dolphins 56    Sony Michel, Chargers vs. Broncos 57    James Cook, Bills @ Chiefs 58    Matt Breida, Giants vs. Ravens

Week 6 RB PPR fantasy projections, rankings from Draft Sharks

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